132.8 miles:
2 hours,
15 minutes
Seasonal route: The road is subject to closure in winter. Running along the eastern Sierra Nevadas, the 133-mile stretch of US 395 between Bishop, Calif., and the junction with SR 89 is loaded with scenic vistas, from an “inland sea” in the middle of the Great Basin Desert to mountain flanks cloaked in juniper and piñon pine. Better yet, the curvy road is in great condition, making it a delight to drive at a leisurely pace.